Annie and Maeve have grown up in very different circumstances. They don't have a whole lot in common, so when they end up in the same class and are essentially forced into a friendship, neither one is very impressed.

Both girls are blind - Maeve since birth, and Annie due to a fairly recent accident. According to most of the adults in their lives, this should be the basis for a beautiful friendship. Annie and Maeve disagree.
When overlapping friends, birthday parties, pesky classmates, school camp, concert auditions and holiday sleepovers conspire to force the girls into hanging out, they realise that they might have more in common than they could have guessed.

Their shared disability isn't the reason they decide to be friends, but they both learn that sometimes it is a true revelation to find someone who totally gets some of the things you're going through.